VRTX Institutional Holdings

Name: VRTX (Vertex Pharmaceuticals) Institutional Holdings — 2026Q1
Creator: SEC EDGAR
License: https://www.sec.gov/data

Vertex Pharmaceuticals · SEC 13F

1,752 institutions hold VRTX, totaling 738.1M shares ($125.5B）.
As of 2026Q1 · SEC EDGAR 13F

Quarterly Changes

2025Q4 → 2026Q1

↑ New Positions (5)

VANGUARD CAPITAL MANAGEMENT LLC $14.8B

VANGUARD PORTFOLIO MANAGEMENT LLC $2.4B

HSBC HOLDINGS PLC $864M

VANGUARD FIDUCIARY TRUST CO $661M

Vanguard Global Advisers, LLC $248M

↑ Increased (5)

BNP PARIBAS ASSET MANAGEMENT Holding S.A. +124589.4%

CWM, LLC +116069.2%

IFM Investors Pty Ltd +100949.3%

BOWEN HANES & CO INC +99794.4%

Daiwa Securities Group Inc. +94131.7%

↓ Decreased (5)

Kentucky Retirement Systems -100.0%

TIAA TRUST, NATIONAL ASSOCIATION -99.8%

Clal Insurance Enterprises Holdings Ltd -99.5%

Fulcrum Asset Management LLP -99.4%

Fideuram Asset Management (Ireland) dac -99.1%

↓ Exited Positions (5)

VANGUARD GROUP INC $11.1B

Winslow Capital Management, LLC $405M

Alyeska Investment Group, L.P. $161M

Carmignac Gestion $87M

Sofinnova Investments, Inc. $75M

All Holders (Top 100)

Rank	Institution	Shares	Value
1	VANGUARD CAPITAL MANAGEMENT LLC	39.3M	$14.8B
2	Capital World Investors	25.4M	$11.3B
3	BlackRock, Inc.	34.9M	$10.8B
4	Capital Research Global Investors	21.1M	$9.4B
5	STATE STREET CORP	13.6M	$5.3B
6	DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main	14.9M	$4.3B
7	BARCLAYS PLC	15.9M	$4.2B
8	MORGAN STANLEY	20.8M	$4.2B
9	JPMORGAN CHASE & CO	16.1M	$3.2B
10	GEODE CAPITAL MANAGEMENT, LLC	7.9M	$2.8B
11	VANGUARD PORTFOLIO MANAGEMENT LLC	9.9M	$2.4B
12	Capital International Investors	5.1M	$2.3B
13	GOLDMAN SACHS GROUP INC	7.6M	$1.9B
14	JANUS HENDERSON GROUP PLC	4.3M	$1.9B
15	LOOMIS SAYLES & CO L P	4.0M	$1.8B
16	ALLIANCEBERNSTEIN L.P.	4.0M	$1.8B
17	NORGES BANK	3.4M	$1.6B
18	WELLINGTON MANAGEMENT GROUP LLP	3.2M	$1.4B
19	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	3.2M	$1.4B
20	BANK OF AMERICA CORP /DE/	9.2M	$1.3B
21	JENNISON ASSOCIATES LLC	3.7M	$1.2B
22	Clearbridge Investments, LLC	2.7M	$1.2B
23	AMERIPRISE FINANCIAL INC	2.7M	$1.2B
24	NORTHERN TRUST CORP	3.2M	$1.2B
25	Invesco Ltd.	2.6M	$1.1B
26	FMR LLC	6.3M	$910M
27	Legal & General Group Plc	2.0M	$874M
28	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	2.5M	$865M
29	HSBC HOLDINGS PLC	1.9M	$864M
30	VICTORY CAPITAL MANAGEMENT INC	1.9M	$843M
31	Bank of New York Mellon Corp	1.8M	$711M
32	DEUTSCHE BANK AG\	1.8M	$689M
33	VANGUARD FIDUCIARY TRUST CO	2.0M	$661M
34	Amundi	1.5M	$658M
35	WCM INVESTMENT MANAGEMENT, LLC	1.1M	$497M
36	ROYAL BANK OF CANADA	1.1M	$497M
37	Nuveen, LLC	1.3M	$486M
38	DIMENSIONAL FUND ADVISORS LP	1.6M	$449M
39	DANSKE BANK A/S	1.0M	$413M
40	EDGEWOOD MANAGEMENT LLC	905K	$404M
41	BNP PARIBAS ASSET MANAGEMENT Holding S.A.	849K	$379M
42	AMERICAN CENTURY COMPANIES INC	813K	$363M
43	UBS Group AG	6.1M	$347M
44	WELLS FARGO & COMPANY/MN	3.8M	$336M
45	Swiss National Bank	890K	$334M
46	CITIGROUP INC	1.9M	$319M
47	Bellevue Group AG	682K	$304M
48	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	1.6M	$296M
49	Sumitomo Mitsui Trust Group, Inc.	614K	$274M
50	Mitsubishi UFJ Asset Management Co., Ltd.	597K	$267M
51	Vanguard Global Advisers, LLC	584K	$248M
52	MANUFACTURERS LIFE INSURANCE COMPANY, THE	584K	$247M
53	NEUBERGER BERMAN GROUP LLC	552K	$246M
54	FRANKLIN RESOURCES INC	551K	$246M
55	Assenagon Asset Management S.A.	537K	$240M
56	National Pension Service	532K	$238M
57	VOYA INVESTMENT MANAGEMENT LLC	539K	$235M
58	B. Metzler seel. Sohn & Co. AG	511K	$228M
59	ENVESTNET ASSET MANAGEMENT INC	573K	$226M
60	California Public Employees Retirement System	503K	$225M
61	Candriam S.C.A.	454K	$204M
62	RAYMOND JAMES FINANCIAL INC	444K	$198M
63	VANGUARD ASSET MANAGEMENT, Ltd	490K	$198M
64	Life Cycle Investment Partners Ltd	440K	$197M
65	RENAISSANCE TECHNOLOGIES LLC	712K	$192M
66	BNP PARIBAS FINANCIAL MARKETS	927K	$192M
67	PRINCIPAL FINANCIAL GROUP INC	427K	$190M
68	RHUMBLINE ADVISERS	510K	$190M
69	Chevy Chase Trust Holdings, LLC	408K	$182M
70	Robeco Institutional Asset Management B.V.	402K	$179M
71	BANK OF MONTREAL /CAN/	390K	$174M
72	TWO SIGMA INVESTMENTS, LP	483K	$170M
73	Zurcher Kantonalbank (Zurich Cantonalbank)	416K	$169M
74	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	442K	$168M
75	ProShare Advisors LLC	384K	$167M
76	CITADEL ADVISORS LLC	1.5M	$165M
77	Russell Investments Group, Ltd.	378K	$164M
78	Universal- Beteiligungs- und Servicegesellschaft mbH	388K	$152M
79	Pictet Asset Management Holding SA	351K	$150M
80	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	327K	$149M
81	MARSHALL WACE, LLP	606K	$145M
82	Bank Julius Baer & Co. Ltd, Zurich	317K	$142M
83	Harding Loevner LP	314K	$140M
84	AMF Tjanstepension AB	313K	$140M
85	FIRST TRUST ADVISORS LP	306K	$137M
86	NEW YORK STATE COMMON RETIREMENT FUND	727K	$136M
87	Cerity Partners LLC	297K	$132M
88	D. E. Shaw & Co., Inc.	1.9M	$131M
89	Rockefeller Capital Management L.P.	286K	$128M
90	NATIONAL BANK OF CANADA /FI/	272K	$122M
91	Swedbank AB	272K	$121M
92	Woodline Partners LP	270K	$121M
93	LPL Financial LLC	279K	$120M
94	ROYAL LONDON ASSET MANAGEMENT LTD	252K	$113M
95	ADAGE CAPITAL PARTNERS GP, L.L.C.	252K	$113M
96	Connor, Clark & Lunn Investment Management Ltd.	252K	$112M
97	Man Group plc	237K	$106M
98	Aberdeen Group plc	233K	$104M
99	TD Asset Management Inc	228K	$102M
100	STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM	225K	$100M

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Data source: SEC EDGAR Form 13F · Updated 2026-07-09